Key result
Baseline ST-T abnormalities predict 11.5-year CHD mortality in middle-aged men but not clearly in women.
Why the study?
The independent contributions of baseline resting ECG ST-T abnormalities to long-term coronary heart disease mortality were explored across sexes.
Does the presence of ST-T abnormalities on resting ECG predict coronary heart disease mortality differently in men versus women without baseline CHD?
Population
9203 white men and 7818 white women aged 40 to 64 years without definite CHD at entry
Comparison
Presence vs absence of baseline resting ECG ST-T abnormalities
Design
Prospective cohort study
Follow-up
11.5 year
Authors
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Baseline ST-T abnormalities may signal higher CHD mortality risk; leaves open their added value in contemporary risk models.
Cohort (n=17,021)
Does the presence of ST-T abnormalities on resting ECG predict coronary heart disease mortality differently in men versus women without baseline CHD?
Baseline ST-T abnormalities on resting ECG independently predict long-term coronary death in middle-aged men, but not clearly in women.
Liao et al. (1987) conducted a cohort in Coronary heart disease (n=17,021). Baseline ST-T abnormalities vs. Absence of ST-T abnormalities was evaluated on 11.5 year coronary heart disease (CHD) mortality. Baseline ST-T abnormalities independently predicted 11.5-year CHD mortality in middle-aged U.S. men, but not clearly in women, despite a higher baseline prevalence in women (12.3% vs 8.1%).
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