Key result
Diabetes mellitus in heart failure patients undergoing LVAD implantation was associated with shorter hospital stays, lower costs, and similar in-hospital mortality compared with non-diabetic patients.
Why the study?
Diabetes mellitus is a recognized risk factor for heart failure, increasing the likelihood of requiring LVAD therapy, but its impact on LVAD outcomes needed assessment.
Does diabetes mellitus impact in-hospital mortality in adult heart failure patients undergoing LVAD implantation?
Cohort (n=11,506)
Yes
Does diabetes mellitus impact in-hospital mortality in adult heart failure patients undergoing LVAD implantation?
In patients undergoing LVAD implantation, the presence of diabetes mellitus does not increase in-hospital mortality and is associated with shorter hospital stays and lower admission costs.
Does not support changing LVAD candidacy or care by diabetes status; leaves open causality and generalizability.
Aim: Diabetes mellitus (DM) is a recognized risk factor for heart failure (HF), increasing the likelihood of requiring left ventricular assist device (LVAD) therapy. Objective: This retrospective cohort study aims to assess the impact of DM on LVAD patients, focusing on in-hospital mortality as the primary outcome. Methods: Utilizing the National Inpatient Sample administrative database, data from 11,506 adult HF patients who underwent LVAD implantation were analyzed. Results: Of the patients, 44.28% had diabetes. Adjusting for various factors, diabetic patients exhibited shorter hospital stays, lower admission costs and similar in-hospital mortality rates compared with non-diabetic patients. Conclusion: These findings enhance our understanding of the risks and benefits of LVAD therapy in patients with refractory HF and DM.
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Obeidat et al. (2023) conducted a cohort in Heart failure requiring left ventricular assist device (LVAD) therapy (n=11,506). Diabetes mellitus vs. Non-diabetic patients was evaluated on In-hospital mortality. Diabetes mellitus in heart failure patients undergoing LVAD implantation was associated with shorter hospital stays, lower costs, and similar in-hospital mortality compared with non-diabetic patients.
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