Key result
Continuous infusion of thoracic epidural bupivacaine significantly reduced postoperative supraventricular tachyarrhythmias compared with epidural morphine (4.3% vs 28.0%; P=0.0497).
Why the study?
Does thoracic epidural bupivacaine reduce postoperative supraventricular tachyarrhythmias compared to epidural morphine in patients undergoing pulmonary resection?
Population
50 patients with lung cancer undergoing pulmonary resection
Comparison
Epidural bupivacaine vs Epidural morphine
Design
RCT, randomized
Follow-up
3 days
Authors
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Thoracic epidural bupivacaine may reduce postoperative supraventricular tachyarrhythmias; leaves open need for confirmatory trials before practice change.
RCT (n=50)
Randomized
Does thoracic epidural bupivacaine reduce postoperative supraventricular tachyarrhythmias compared to epidural morphine in patients undergoing pulmonary resection?
Absolute Event Rate: 4.3% vs 28%
p-value: p=0.0497
Thoracic epidural bupivacaine reduces the incidence of postoperative supraventricular tachyarrhythmias after pulmonary resection compared to epidural morphine.
Oka et al. (2001) conducted an RCT in Lung cancer undergoing pulmonary resection (n=50). Thoracic epidural bupivacaine vs. Epidural morphine was evaluated on Incidence of postoperative tachyarrhythmias (p=0.0497). Continuous infusion of thoracic epidural bupivacaine significantly reduced postoperative supraventricular tachyarrhythmias compared with epidural morphine (4.3% vs 28.0%; P=0.0497).
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