Randomized trial demonstrates effective synthesis of 1-sulfonyl-1,2,3-triazoles, indicating a practical approach for chemists.
An efficient room-temperature method for the synthesis of 1-sulfonyl-1,2,3-triazoles from in situ generated copper(I) acetylides and sulfonyl azides is described. The copper(I) thiophene-2-carboxylate (CuTC) catalyst produces the title compounds under both nonbasic anhydrous and aqueous conditions in good yields.
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Raushel et al. (2010) studied this question.
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