Key result
Impaired heart rate variability (SDNN <10 ms) was an independent negative prognosticator for overall survival in patients with brain metastasis (HR 2.204).
Why the study?
Does impaired heart rate variability (SDNN <10 ms) predict poor overall survival in patients with brain metastasis?
Population
40 patients with brain metastasis who had not undergone previous brain operation or radiotherapy
Design
Cohort
Authors
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May aid prognostication in brain metastasis; leaves open prospective validation before clinical use.
Cohort (n=40)
Does impaired heart rate variability (SDNN <10 ms) predict poor overall survival in patients with brain metastasis?
Hazard Ratio: 2.204
p-value: p=0.004
Impaired heart rate variability (SDNN <10 ms) is an independent predictor of poor overall survival in patients with brain metastasis.
Wang et al. (2013) conducted a cohort in Brain metastasis (n=40). Impaired heart rate variability (SDNN <10 ms) was evaluated on overall survival (OS) (HR 2.204, p=0.004). Impaired heart rate variability (SDNN <10 ms) was an independent negative prognosticator for overall survival in patients with brain metastasis (HR 2.204).
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