Key result
Acetylcholine testing provoked experimental reproduction of left ventricular apical ballooning in 1 patient and extensive angiographic vasospasm in 2 others among a series of 4 cases.
Why the study?
Does acetylcholine testing provoke coronary vasospasm and reproduce LVAB in patients with transient left ventricular apical ballooning?
Case Report (n=4)
Does acetylcholine testing provoke coronary vasospasm and reproduce LVAB in patients with transient left ventricular apical ballooning?
Acetylcholine testing suggests that transient left ventricular apical ballooning may be caused by severe, sustained spasm of multiple coronary vessels.
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Acetylcholine testing may identify spasm in LVAB cases; leaves open need for prospective validation before diagnostic adoption.
Paolo Angelini (2008) conducted a case report in Transient left ventricular apical ballooning (LVAB) cardiomyopathy (n=4). Acetylcholine testing was evaluated. Acetylcholine testing provoked experimental reproduction of left ventricular apical ballooning in 1 patient and extensive angiographic vasospasm in 2 others among a series of 4 cases.
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