Key result
High-normal blood pressure was associated with higher resting muscle sympathetic nerve activity compared to optimal blood pressure (26 vs 18 bursts/min, p<0.05), but normal responses to stress tests.
Why the study?
Is high-normal blood pressure associated with increased resting sympathetic activity and altered responses to stress tests compared to optimal blood pressure?
Population
30 subjects including 18 with high-normal BP and 12 with optimal BP, matched for age and body mass index.
Design
Cross-sectional
Authors
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High-normal BP may reflect subclinical sympathetic activation; leaves open mechanistic and prognostic implications requiring prospective study.
Cross-Sectional (n=30)
Is high-normal blood pressure associated with increased resting sympathetic activity and altered responses to stress tests compared to optimal blood pressure?
Absolute Event Rate: 26% vs 18%
p-value: p=<0.05
Hering et al. (2013) conducted a cross-sectional in High-normal blood pressure (n=30). High-normal blood pressure vs. Optimal blood pressure (< 120/80 mmHg) was evaluated on Resting muscle sympathetic nerve activity (MSNA) (p=<0.05). High-normal blood pressure was associated with higher resting muscle sympathetic nerve activity compared to optimal blood pressure (26 vs 18 bursts/min, p<0.05), but normal responses to stress tests.
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