Key result
Afternoon measurement at 14:00 hours did not significantly alter vascular function outcomes compared to 09:00 hours, including IMT (P=0.27), PWV (P=0.52), AIX (P=0.35), and FMD (P=0.70).
Why the study?
Does the time of day (09:00 vs 14:00) affect the outcomes of non-invasive measurements of vascular function in healthy volunteers?
Population
19 healthy volunteers
Comparison
Non-invasive measurements of vascular function… vs Non-invasive measurements of vascular function…
Design
Cross-sectional
Authors
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Time-of-day effects on vascular measures remain uncertain; leaves open standardization of timing in future studies.
Observational (n=19)
Does the time of day (09:00 vs 14:00) affect the outcomes of non-invasive measurements of vascular function in healthy volunteers?
p-value: p=0.27
Non-invasive measurements of vascular function (IMT, PWV, AIX, FMD) are not significantly confounded by the time of day (morning vs afternoon) in healthy volunteers when exogenous conditions are controlled.
Avest et al. (2005) conducted an observational in Healthy (n=19). Afternoon measurement (14:00 hours) vs. Morning measurement (09:00 hours) was evaluated on Absolute difference in intima-media thickness (IMT) between 09:00 and 14:00 hours compared with repeated measurements at 09:00 hours (p=0.27). Afternoon measurement at 14:00 hours did not significantly alter vascular function outcomes compared to 09:00 hours, including IMT (P=0.27), PWV (P=0.52), AIX (P=0.35), and FMD (P=0.70).
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