June 1, 1989Hypertension
Endothelium and control of vascular function. State of the Art lecture.
Key result
Endothelial cells modulate vascular function by releasing dilator and constrictor substances, with the release of relaxing factors being blunted in hypertensive blood vessels.
Design
Review
Authors
Discussion
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Implication
Endothelial balance assessment may guide hypertension evaluation; leaves open targeted interventions for prospective trials.
PICO
P
Population
Hypertension
E
Exposure / Comparator
Endothelial cells
This state-of-the-art review highlights the fundamental role of the endothelium in regulating vascular tone through the release of vasoactive factors, providing a basis for understanding vascular dysfunction in hypertension.
Cite This Study
Paul M. Vanhoutte (1989) conducted a review in Hypertension. Endothelial cells was evaluated. Endothelial cells modulate vascular function by releasing dilator and constrictor substances, with the release of relaxing factors being blunted in hypertensive blood vessels.