Key result
Nonlinear interactions between TGF and myogenic oscillations were observed in Sprague-Dawley rats but not in spontaneously hypertensive rats due to reduced myogenic oscillation magnitude.
Population
Sprague-Dawley rats (n=13) and spontaneously hypertensive rats (SHR, n=13)
Design
Preclinical
Authors
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Fast myogenic oscillations rarely detected in tubular pressure; leaves open their role in renal autoregulation.
Nonlinear interactions exist between TGF and myogenic oscillations in renal autoregulation in normotensive rats, but are reduced or absent in spontaneously hypertensive rats.
Chon et al. (2004) studied Renal autoregulation (n=26). Spontaneously hypertensive rats (SHR) vs. Sprague-Dawley rats was evaluated on Nonlinear interactions between TGF and myogenic oscillations in stop-flow pressure. Nonlinear interactions between TGF and myogenic oscillations were observed in Sprague-Dawley rats but not in spontaneously hypertensive rats due to reduced myogenic oscillation magnitude.
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