Key result
A 44-year-old woman with severe orthostatic hypertension demonstrated increased pressor sensitivity to norepinephrine (11 to 14 times normal), indicating vascular adrenergic hypersensitivity.
Case Report (n=1)
This case report identifies vascular adrenergic hypersensitivity as a potential mechanism for severe orthostatic hypertension.
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Orthostatic hypertension cases remain rare and mechanistically unclear; leaves open prevalence, criteria, and management trials.
Benowitz et al. (1996) conducted a case report in Orthostatic hypertension (n=1). Vascular adrenergic hypersensitivity was evaluated on Autonomic nervous system function (pressor sensitivity). A 44-year-old woman with severe orthostatic hypertension demonstrated increased pressor sensitivity to norepinephrine (11 to 14 times normal), indicating vascular adrenergic hypersensitivity.
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