Key result
Female sex (OR 5.58; 95% CI 4.20-7.43) and morbid obesity (OR 14.49; 95% CI 6.99-30.03) were significant independent factors for the use of large tidal volumes during general anaesthesia.
Why the study?
What is the incidence of and what patient factors are associated with the use of large intra-operative tidal volumes during general anaesthesia?
Observational (n=2,960)
Yes
What is the incidence of and what patient factors are associated with the use of large intra-operative tidal volumes during general anaesthesia?
Odds Ratio: 5.58 (95% CI 4.2–7.43)
p-value: p=≤ 0.005
A significant proportion of patients, particularly females and those with higher body mass index, receive potentially excessive tidal volumes during general anaesthesia.
Observational ventilation data should not change practice; leaves open links between tidal volume choice and perioperative outcomes.
We conducted an observational prospective multicenter study to describe the practices of mechanical ventilation, to determine the incidence of use of large intra-operative tidal volumes (≥10 ml.kg(-1) of ideal body weight) and to identify patient factors associated with this practice. Of the 2960 patients studied in 97 anaesthesia units from 49 hospitals, volume controlled mode was the most commonly used (85%). The mean (SD) tidal volume was 533 (82) ml; 7.7 (1.3) ml.kg(-1) (actual weight) and 8.8 (1.4) ml.kg(-1) (ideal body weight)). The lungs of 381 (18%) patients were ventilated with a tidal volume>10 ml.kg(-1) ideal body weight. Being female (OR 5.58 (95% CI 4.20-7.43)) and by logistic regression, underweight (OR 0.06 (95% CI 0.01-0.45)), overweight (OR 1.98 (95% CI 1.49-2.65)), obese (OR 5.02 (95% CI 3.51-7.16)), severely obese (OR 10.12 (95% CI 5.79-17.68)) and morbidly obese (OR 14.49 (95% CI 6.99-30.03)) were the significant (p ≤ 0.005) independent factors for the use of large tidal volumes during anaesthesia.
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Jaber et al. (2012) conducted an observational in General anaesthesia (n=2,960). Female sex and obesity was evaluated on Use of large intra-operative tidal volumes (≥10 ml.kg(-1) of ideal body weight) (OR 5.58, 95% CI 4.20-7.43, p=≤ 0.005). Female sex (OR 5.58; 95% CI 4.20-7.43) and morbid obesity (OR 14.49; 95% CI 6.99-30.03) were significant independent factors for the use of large tidal volumes during general anaesthesia.
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