Key result
Metabolic syndrome was present in 34.8% of young patients (≤50 years) with acute coronary syndrome in Bangladesh, with a significantly higher prevalence in females (48.8%) compared to males (30.4%).
Why the study?
Metabolic syndrome is a significant CAD risk factor highly prevalent in South Asian countries including Bangladesh and affects young people, but data on its prevalence and components in early-onset ACS were needed.
What is the prevalence of metabolic syndrome and its components among early-age onset acute coronary syndrome patients in Bangladesh?
Cross-Sectional (n=678)
No
What is the prevalence of metabolic syndrome and its components among early-age onset acute coronary syndrome patients in Bangladesh?
Metabolic syndrome is highly prevalent (34.8%) among young (≤50 years) ACS patients in Bangladesh, driven primarily by low HDL and high triglycerides, highlighting these as key targets for early intervention.
MetS prevalence in young Bangladeshi ACS patients supports screening; leaves open whether targeted interventions improve outcomes.
Aim: Metabolic Syndrome (MetS), a significant risk factor for coronary artery disease (CAD), is now highly prevalent in South Asian countries, including Bangladesh. The diseases also affect young people. A large number of young populations with acute coronary syndrome (ACS) have MetS. The aim of this study was to determine the prevalence of MetS and the combination of components in patients with early age onset ACS (age ≤50 years). Methods: This prospective study comprised 678 consecutive patients age ≤50 years hospitalized for ACS during 2012-2013. The patients were categorized according to the criteria stated in the latest joint statement for the global definition of MetS. Results: Among 678 ACS patients, 236 (34.8%) patients have filled the criteria of MetS. The mean age was 42.4 ± 0.28 years. The prevalence of MetS was higher in females than in males (48.8% vs. 30.4%, p < 0.001). One component of MetS was found in 26.4%, two components in 29.8%, three or more components in 34.8% of young ACS study participants. Among the various components of MetS, low HDL and high TG were the crucial common components of MetS in young ACS patients in Bangladesh (low HDL: 51.9%, high TG: 44.8%). Conclusions: We conclude that the prevalence of MetSin patients with early age onset ACS (age ≤50 years) is high in Bangladesh. Since Low HDL and high TG are the most common components of MetSin our study, these biochemical parameters would be a clinical target for early treatment. Strategies are needed for the early detection and treatment of cardio-metabolic risk factors to prevent coronary artery disease progression and prognosis.
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Jesmin et al. (2021) conducted a cross-sectional in Early-age onset Acute Coronary Syndrome (ACS) (n=678). Early-age onset Acute Coronary Syndrome was evaluated on Prevalence of Metabolic Syndrome. Metabolic syndrome was present in 34.8% of young patients (≤50 years) with acute coronary syndrome in Bangladesh, with a significantly higher prevalence in females (48.8%) compared to males (30.4%).
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