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October 6, 2011Clinical and Experimental Hypertension

Prehypertension and hypertension were associated with autonomic imbalance, characterized by vagal inhibition in prehypertensives and prominent vagal withdrawal in hypertensives.

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Why the study?

How does sympathovagal balance change across normotensive, prehypertensive, and hypertensive states?

Population

91 subjects including normotensives, prehypertensives, and hypertensives in an Indian population.

Design

Cross-sectional

Key result

Prehypertension and hypertension were associated with autonomic imbalance, characterized by vagal inhibition in prehypertensives and prominent vagal withdrawal in hypertensives.

Authors

GPG K PalCAC AdithanDAD Amudharaj

Discussion

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Overview

Sympathovagal imbalance may mark prehypertension progression; leaves open whether HRV modulation alters hypertension risk.

Study Design

Type

Observational (n=91)

Structured PICO

How does sympathovagal balance change across normotensive, prehypertensive, and hypertensive states?

P
Population
91 subjects comprising 32 normotensives, 28 prehypertensives, and 31 hypertensives assessed for sympathovagal imbalance.
C
Comparator
Normotensive subjects (n=32)
O
Outcome
Sympathovagal imbalance assessed by spectral indices of heart rate variability (HRV) including LF-HF ratiosurrogate

Vagal inhibition plays a critical role in the alteration of sympathovagal balance during the development of clinical hypertension from prehypertension.

Cite This Study

Pal et al. (2011) conducted an observational in Prehypertension and Hypertension (n=91). Prehypertension and hypertension vs. Normotension was evaluated on Sympathovagal imbalance (spectral indices of HRV). Prehypertension and hypertension were associated with autonomic imbalance, characterized by vagal inhibition in prehypertensives and prominent vagal withdrawal in hypertensives.

synapsesocial.com/papers/6a64ee988d00ec7015f699f2https://doi.org/10.3109/10641963.2010.549275
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