Key result
Prosthetic valve endocarditis was associated with significantly higher rates of septic shock (7.4% vs 1%; P=0.036) and recurrent endocarditis (8.8% vs 1%; P=0.016) compared to native valve endocarditis.
Why the study?
Infective endocarditis is a heterogeneous infection, and the authors aimed to compare the demographic characteristics, causative microorganisms, treatment, and prognosis of prosthetic versus native valve endocarditis.
Does prosthetic valve endocarditis have different clinical outcomes compared to native valve endocarditis in patients with infective endocarditis?
Population
173 consecutive patients diagnosed with infective endocarditis across two hospitals
Comparison
Prosthetic valve endocarditis vs native valve endocarditis
Design
Retrospective multicenter study
Follow-up
6 months
Authors
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Cohort (n=173)
Yes
Does prosthetic valve endocarditis have different clinical outcomes compared to native valve endocarditis in patients with infective endocarditis?
Absolute Event Rate: 7.4% vs 1%
p-value: p=.036
Ak et al. (2021) conducted a cohort in Infective endocarditis (IE) (n=173). Prosthetic valve endocarditis vs. Native valve endocarditis was evaluated on Septic shock (p=.036). Prosthetic valve endocarditis was associated with significantly higher rates of septic shock (7.4% vs 1%; P=0.036) and recurrent endocarditis (8.8% vs 1%; P=0.016) compared to native valve endocarditis.
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