January 1, 1960Thrombosis and Haemostasis

Studies on the Metabolism of Human Blood Platelets in Relation to Clot Retraction

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Key result

No clinical study data is present in the provided text, which consists only of journal editorial board information.

Population

Human blood platelets

Comparison

Addition of thrombin and/or glucose, inhibition… vs Control conditions

Design

Preclinical

Authors

MBM Bettex-GallandUniversity of Bern ELE. F. LüscherUniversity of Geneva

Discussion

Member takes

Implication

Thrombin effects on platelet respiration in EDTA media leave open metabolic roles in thrombosis; hypothesis-generating for contemporary studies.

Structured PICO

Population

Human blood platelets

Intervention

Addition of thrombin and/or glucose, inhibition of glycolysis

Comparator

Control conditions (without thrombin, without glucose)

Outcome

Respiratory activity, glycolytic activity, ATP levels, and clot retractionsurrogate

Platelet clot retraction is dependent on ATP levels generated primarily through glycolysis when glucose is present.

Cite This Study

Bettex-Galland et al. (1960) studied this question. No clinical study data is present in the provided text, which consists only of journal editorial board information.

synapsesocial.com/papers/6a650940dfe9f9fc9bef3fe4 https://doi.org/10.1055/s-0038-1654495

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Implication

Thrombin effects on platelet respiration in EDTA media leave open metabolic roles in thrombosis; hypothesis-generating for contemporary studies.

Studies on the Metabolism of Human Blood Platelets in Relation to Clot Retraction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Studies on the Metabolism of Human Blood Platelets in Relation to Clot Retraction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider