Key result
Carotid-femoral pulse wave velocity is the gold standard for assessing arterial stiffness and serves as an independent predictor of cardiovascular events, though evidence for its use as a therapeutic target remains limited.
Carotid-femoral pulse wave velocity is a valuable tool for assessing arterial stiffness and improving cardiovascular risk stratification in clinical practice.
Aortic PWV may refine CV risk reclassification; leaves open prospective validation before routine clinical adoption.
Carotid-femoral (aortic) pulse wave velocity (PWV) is the modern benchmark for the assessment of arterial stiffness. Current European hypertension guidelines acknowledge the good cardiovascular (CV) predictive value, reproducibility and cost-effectiveness of PWV. Aortic PWV is an asset to classical cardiovascular risk scores and can reclassify patients. Reference values for carotid-femoral PWV have been established. Together with standardisation of user procedures and patient conditions, these reference values are needed for an appropriate use of aortic stiffness in daily clinical practice. Finally, the existing evidence for a decrease in CV risk by decreasing aortic stiffness is discussed.
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Luc Van Bortel (2016) conducted a review in Cardiovascular disease. Carotid-femoral pulse wave velocity (aortic stiffness) was evaluated. Carotid-femoral pulse wave velocity is the gold standard for assessing arterial stiffness and serves as an independent predictor of cardiovascular events, though evidence for its use as a therapeutic target remains limited.
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