Metal nanoparticles synthesis through natural phenolic acids

For being applied in medicine as therapeutic agents, nanostructures need to be biocompatible and eco-friendly. Plant-derived phenolic acids have been utilised for green synthesis of metallic or metallic oxide nanoparticles (NPs). The phenolic acids play role as both reducing agents and stabilisers in the process of NPs synthesis. Many experiments have been dedicated to develop efficient green synthesis techniques for producing metal NPs. Using phenolic acids represents a reproducible, simple, profitable, and cost-effective strategy to synthesise metal NPs. As a phytochemical for metal NPs synthesis, phenolic acids are antioxidants that represent many health benefits. However, limited studies have been dedicated to the synthesis and characterisation of NPs produced by phenolic acids. Thus, this review focused on phenolic acids mediated nanomaterial synthesis and its biomedical applications. It should be noted the mechanism of metal ion bioreduction, phenolic acids surface adsorption, characterisation, and toxicity of metal NPs made with different phenolic acids have been discussed in this review.