Key result
Fetal growth restriction was associated with significantly lower high frequency power during fetal quiescence compared to healthy fetuses (Ratio 0.56; 95% CI 0.32-0.98).
Why the study?
The study aimed to assess the association between fetal growth restriction and fetal heart rate variability in relation to fetal movements.
Does fetal growth restriction alter fetal heart rate variability during respiratory activity and quiescence compared to average for gestational age fetuses?
Population
14 growth-restricted fetuses and 22 healthy control fetuses
Comparison
Fetal growth restriction vs average for gestational age
Design
Prospective observational cohort study
Authors
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FGR may suppress fetal vagal activity during quiescence while preserving RSA; leaves open whether NI-FECG parameters improve surveillance in growth-restricted pregnancies.
Cohort (n=36)
Does fetal growth restriction alter fetal heart rate variability during respiratory activity and quiescence compared to average for gestational age fetuses?
Effect estimate: Ratio 0.56 (95% CI 0.32-0.98)
Fetal growth restriction is associated with impaired cardiac vagal activity during fetal quiescence, despite preserved respiratory sinus arrhythmia.
Zizzo et al. (2022) conducted a cohort in Fetal growth restriction (n=36). Fetal growth restriction vs. Average for gestational age (AGA) fetuses was evaluated on High frequency (HF) power during fetal quiescence (Ratio 0.56, 95% CI 0.32-0.98). Fetal growth restriction was associated with significantly lower high frequency power during fetal quiescence compared to healthy fetuses (Ratio 0.56; 95% CI 0.32-0.98).
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