November 12, 2023EMERGENCY MEDICINEOpen Access

Prospects for the study of some electrophysiological parameters in the diagnosis of fetal growth restriction

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Why the study?

Traditional ultrasound and Doppler diagnostics for fetal growth restriction require expensive equipment and lengthy specialist training, prompting evaluation of non-invasive fetal electrocardiography.

Does non-invasive fetal electrocardiography identify differences in heart rate variability and morphological parameters in fetuses with growth restriction compared to healthy fetuses?

Comparison

108 women with fetal growth restriction vs 112 with healthy fetuses

Authors

İLİgor LakhnoKharkiv State Academy of Culture АМА. В. МартыненкоKuban State University GRGianfranco RaimondiSapienza University of Rome

Discussion

Member takes

Implication

Noninvasive fetal ECG may lower screening costs; leaves open diagnostic accuracy versus ultrasound in prospective studies.

Structured PICO

Does non-invasive fetal electrocardiography identify differences in heart rate variability and morphological parameters in fetuses with growth restriction compared to healthy fetuses?

Population

220 pregnant women aged 18 to 40 years at 24–41 weeks of gestation, divided into 108 women with fetal growth restriction (Group I) and 112 patients with healthy fetuses (Group II). Excluded: genetic anomalies, fetal malformations, multiple pregnancy, and severe extragenital pathology.

Intervention

Non-invasive fetal electrocardiography recorded in abdominal lead for 30–60 minutes

Comparator

Healthy fetuses (Group II) compared to fetuses with fetal growth restriction (Group I)

Outcome

Indices of heart rate variability (SDNN, SI, TP, LF, LF/HF, AC/DC) and morphological parameters of the pQRST complex (QTc duration, QRS complex width, T/QRS ratio)surrogate

Non-invasive fetal electrocardiography reveals significant alterations in heart rate variability and repolarization parameters in fetuses with growth restriction, reflecting autonomic dysregulation and myocardial ischemia.

Limitations

Low signal-to-noise ratio in abdominal signals, especially between 28-33 weeks of gestation
Requirement for manual correction of QRS averaging intervals and peak markers due to low amplitude of p and T waves
Manual measurement required for the pR parameter
Changes in fetal ECG parameters are not maximally specific for fetal growth restriction and may also indicate fetal distress

Cite This Study

Lakhno et al. (2023) studied this question.

synapsesocial.com/papers/6a96943517cb0e8b160e2803 https://doi.org/10.22141/2224-0586.19.6.2023.1619

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Prospects for the study of some electrophysiological parameters in the diagnosis of fetal growth restriction

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Prospects for the study of some electrophysiological parameters in the diagnosis of fetal growth restriction

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider