Key result
Overweight and obese patients with established cardiovascular diseases appear to have a better clinical prognosis than lean patients, though this obesity paradox may be driven by limitations of BMI and confounding factors.
Why the study?
Whether the obesity paradox exists in patients with established cardiovascular diseases remains a subject of ongoing clinical debate.
This review highlights the ongoing debate and potential explanations for the obesity paradox in cardiovascular disease, where higher body mass index is paradoxically associated with better clinical outcomes.
Should not alter weight management goals in secondary prevention; leaves open whether the obesity paradox reflects true biology or.
In recent years, clinical evidence suggests that obese and overweight people with established cardiovascular diseases (CVDs) seem to have a better prognosis compared with lean patients. This phenomenon has been described as the 'obesity paradox', but there are also those who disagree with this seemingly deviant view, its existence remains a point of debate. This review tries to summarize the latest research progress of obesity paradox in CVDs and concludes with some explanations for this puzzling phenomenon.
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Zhong Chen (2020) conducted a review in Cardiovascular Diseases. Overweight and obesity vs. Normal weight was evaluated. Overweight and obese patients with established cardiovascular diseases appear to have a better clinical prognosis than lean patients, though this obesity paradox may be driven by limitations of BMI and confounding factors.
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