Key result
The high-resolution crystal structure of the Ad41 short fiber head reveals shorter loops, a highly disordered pepsin-sensitive beta-strand, and an AB loop deletion incompatible with CAR binding.
Population
Human enteric adenovirus serotype 41 (Ad41) short fiber head
Design
Preclinical
Authors
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Crystal structure of Ad41 short fiber reveals distinct features; leaves open its functional role in enteric infection.
The crystal structure of the Ad41 short fiber head reveals unique features, including pepsin sensitivity and inability to bind CAR, which may relate to its function in the intestinal tract.
Seiradake et al. (2005) studied Human enteric adenovirus serotype 41 (Ad41). Crystal structure determination was evaluated on Crystal structure of the short fiber head. The high-resolution crystal structure of the Ad41 short fiber head reveals shorter loops, a highly disordered pepsin-sensitive beta-strand, and an AB loop deletion incompatible with CAR binding.
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