Key result
Type II diabetes mellitus in patients with coronary artery disease was associated with significantly increased maximum clot elasticity compared to non-diabetic CAD patients (233.6 vs 186.7; p=0.03).
Why the study?
Does coagulation status differ between coronary artery disease patients with and without type II diabetes mellitus when measured by PFA-100 and ROTEM?
Population
Patients with documented coronary artery disease and type II diabetes mellitus, and non-diabetic patients…
Comparison
Assessment of coagulation status using PFA-100®… vs Non-diabetic patients with coronary artery…
Design
Cross-sectional
Authors
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Comparable platelet function in CAD with versus without diabetes; leaves open diabetes-specific effects on thrombotic risk.
Observational
Does coagulation status differ between coronary artery disease patients with and without type II diabetes mellitus when measured by PFA-100 and ROTEM?
Absolute Event Rate: 233.6% vs 186.7%
p-value: p=0.03
ROTEM analysis indicates increased coagulability in patients with coronary artery disease and diabetes mellitus compared to non-diabetic CAD patients.
Feuring et al. (2010) conducted an observational in Coronary artery disease with and without type II diabetes mellitus. Type II diabetes mellitus vs. Non-diabetic coronary artery disease was evaluated on Maximum clot elasticity (MCE) measured with the EXTEM reagent (p=0.03). Type II diabetes mellitus in patients with coronary artery disease was associated with significantly increased maximum clot elasticity compared to non-diabetic CAD patients (233.6 vs 186.7; p=0.03).
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