Key result
Murray's law-based outlet boundary condition returned the most physiologically accurate haemodynamic results when compared to in vivo data in a subject-specific rabbit aorta model.
Population
Subject-specific rabbit aorta configuration (computational model)
Comparison
Various inlet and outlet boundary conditions vs Available in vivo data
Design
Preclinical
Authors
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Boundary condition sensitivity requires caution in CFD analyses; leaves open standardized protocols for reliable cardiovascular disease prediction.
This computational study demonstrates that the choice of outlet boundary conditions significantly impacts haemodynamic metrics in cardiovascular models, with Murray's law-based conditions providing the most physiologically accurate results.
McElroy et al. (2017) studied Cardiovascular diseases. Various inlet and outlet boundary conditions in computational fluid dynamics vs. In vivo data and alternative boundary conditions was evaluated on Shear rate-based haemodynamic metrics. Murray's law-based outlet boundary condition returned the most physiologically accurate haemodynamic results when compared to in vivo data in a subject-specific rabbit aorta model.
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