Key result
Chronic baroreceptor unloading results in a sustained increase in mean arterial pressure, suggesting that the role of baroreceptors in long-term blood pressure control needs to be revisited.
Why the study?
Does chronic baroreceptor unloading affect the long-term control of mean arterial pressure in experimental animals?
Population
Intact experimental animals
Design
Review
Authors
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Challenges baroreceptor irrelevance for long-term MAP; leaves open human translation and clinical relevance.
Does chronic baroreceptor unloading affect the long-term control of mean arterial pressure in experimental animals?
This review challenges the prevailing consensus by suggesting that arterial baroreceptors play a significant role in the long-term control of blood pressure.
T. N. Thrasher (2004) conducted a review in Blood pressure control. Chronic baroreceptor unloading was evaluated on Mean arterial pressure (MAP). Chronic baroreceptor unloading results in a sustained increase in mean arterial pressure, suggesting that the role of baroreceptors in long-term blood pressure control needs to be revisited.
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