December 7, 1984Science
Nucleotide Sequences of the Human and Mouse Atrial Natriuretic Factor Genes
Key result
Cloning and sequencing of the human and mouse atrial natriuretic factor genes revealed highly conserved 5' flanking sequences and proANF coding regions, suggesting a role in gene regulation.
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Discussion
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Implication
No immediate clinical impact; leaves open functional validation of ANF regulatory sequences in cardiovascular models.
Key Points
Key points are not available for this paper at this time.
Cite This Study
Seidman et al. (1984) studied this question. Cloning and sequencing of the human and mouse atrial natriuretic factor genes revealed highly conserved 5' flanking sequences and proANF coding regions, suggesting a role in gene regulation.