What question did this study set out to answer?

The aim is to evaluate the feasibility and safety of fertility preservation procedures in very young children undergoing gonadotoxic therapy.

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

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Retrospective cohort study shows surgical fertility preservation is safe in very young children, suggesting early integration in care.

The aim is to evaluate the feasibility and safety of fertility preservation procedures in very young children undergoing gonadotoxic therapy.
Retrospective analysis of patients < 18 years undergoing surgical fertility preservation at Goethe-University Hospital from 2014 to 2025
Comparison of outcomes between children < 48 months and older patients
Inclusion of 52 females and 30 males with specific procedural types (laparoscopic hemiovarectomy and open testicular tissue retrieval)
Overall complication rates were 30.8% in females and 53.3% in males, decreasing to 5.8% and 10.0% after excluding disease-related transfusions.
No complications occurred in patients < 48 months, with rates not differing significantly between age groups.
No major complications (Clavien-Dindo ≥ III) were observed, and procedure duration and postoperative stays were comparable across age groups.

Saalabian et al. (2026) studied this question.

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