What question did this study set out to answer?

This study aims to compare artificial intelligence-based risk prediction models with human-based microscopy in predicting malignant transformation in oral epithelial dysplasia.

July 26, 2026Journal of Oral Pathology and MedicineOpen Access

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence‐Based Risk Models and Pathologist‐Based Microscopy

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Authors

DADiele Carine Barreto ArantesFaculdade de Ciências Médicas de Minas Gerais LDLucas Monteiro DelgadoUniversidade Federal de Minas Gerais MSMarília de Marco Pinto Paiva dos SantosFaculdade São Leopoldo Mandic

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Implication

Systematic review evaluates AI versus human microscopy for predicting malignant transformation in oral dysplasia, indicating improved decision-making capacity.

Key Points

This study aims to compare artificial intelligence-based risk prediction models with human-based microscopy in predicting malignant transformation in oral epithelial dysplasia.
Systematic review and meta-analysis of 32 studies (9 AI-based, 23 human-based) from 1998 to 2026.
Focus on oral leukoplakia, erythroleukoplakia, and erythroplakia with AI approaches utilizing machine learning and deep learning techniques.
Data analyzed included odds ratios for predicting malignant transformation.
AI models demonstrated strong discriminative performance with a pooled odds ratio of 12.64 (95% CI: 5.65–28.26).
Human evaluation showed a significant association with malignant transformation (OR = 3.42; 95% CI: 2.07–5.68).
AI models had higher specificity and consistency, while sensitivity levels were comparable to human assessments.

Cite This Study

Arantes et al. (2026) studied this question.

synapsesocial.com/papers/6a65a3e4d3aea3239cd76d8d https://doi.org/10.1111/jop.70168

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Implication

Systematic review evaluates AI versus human microscopy for predicting malignant transformation in oral dysplasia, indicating improved decision-making capacity.

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence‐Based Risk Models and Pathologist‐Based Microscopy

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Cite This Study

Predicting Malignant Transformation in Oral Epithelial Dysplasia: A Systematic Comparison of Artificial Intelligence‐Based Risk Models and Pathologist‐Based Microscopy

Discussion

Member takes

Implication

Key Points

Cite This Study

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