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July 26, 2026PLoS ONEOpen Access

Global lung cancer burden, trends, and projections from 2010 to 2050: A population-level severity framework integrating DALYs-per-case and mortality-to-incidence ratio

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Authors

OFOmar FreihatMAMaria AamirZCZsolt Cselik

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Overview

Global ecological analysis quantifies lung cancer burden and projections, highlighting severity inequities.

Key Points

  • This study aims to quantify the global burden of lung cancer and project future trends using a severity framework.
  • Conducted a global ecological analysis across 185 countries using harmonized data from various sources.
  • Evaluated lung cancer burden through metrics including incident cases, deaths, and DALYs.
  • Projected future burden to 2050 under demographic change and trend-based scenarios.
  • In 2022, there were approximately 2.48 million new lung cancer cases and 1.82 million deaths, with ASIR at 23.6 per 100,000.
  • Projected increases in lung cancer burden by 2050, especially in low-resource countries under both scenarios.
  • Higher DALYs-per-case correlate moderately with mortality-to-incidence ratios, indicating variability in disease severity.

Cite This Study

Freihat et al. (2026) studied this question.

synapsesocial.com/papers/6a65a49fd3aea3239cd7722bhttps://doi.org/10.1371/journal.pone.0354350
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