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November 12, 2025Journal of Evidence-Based Medicine

Epidemiological Trends and Disease Burden of Tracheal, Bronchial, and Lung Cancer in China and Globally From 1990 to 2021: Results From the Global Burden of Disease Study 2021

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Authors

QXQianjie XuXLXiaosheng LiLWLulu Wang

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Overview

Epidemiological analysis reveals rising lung cancer incidence and mortality worldwide, highlighting economic influences and environmental exposure risks.

Key Points

  • This research describes trends in the incidence and burden of tracheal and lung cancer globally and in China.
  • Analyzed Global Burden of Disease 2021 data for incidence, mortality, and disability-adjusted life years
  • Employed age‐period‐cohort model to assess demographic influences
  • Utilized Joinpoint regression for trend analysis
  • Conducted correlation analysis with economic development levels
  • In 2021, global age-standardized incidence rate was 26 per 100,000 population
  • Significantly higher TBL rates observed in males compared to females across all regions
  • Incidence and disease burden increased notably after age 45, peaking after 85
  • Higher economic levels correlate with increased TBL incidence and burden
  • Notable upward trends in lower economic regions signal growing concerns.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/692523d9c0ce034ddc3557c7https://doi.org/10.1111/jebm.70087
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Also Consider

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  2. 2Global lung cancer burden, trends, and projections from 2010 to 2050: A population-level severity framework integrating DALYs-per-case and mortality-to-incidence ratio2026
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  4. 4Abstract 4851: Burden and inequality of early-onset tracheal bronchus, and lung cancer in US, China, and India: A trend and comparison analysis2024
  5. 5Global burden and trends of tracheal, bronchus, and lung cancer attributed to occupational exposure to polycyclic aromatic hydrocarbons in regions with different sociodemographic index, 1990–20212026