Key result
Aortic pulse wave velocity measured by flow-sensitive 4D MRI was significantly higher in patients with aortic atherosclerosis compared to volunteers (5.8 vs 3.8 m/s; P=0.02).
Why the study?
Does flow-sensitive 4D MRI reliably measure aortic pulse wave velocity and correlate with clinical characteristics in patients with aortic atherosclerosis?
Observational (n=98)
Does flow-sensitive 4D MRI reliably measure aortic pulse wave velocity and correlate with clinical characteristics in patients with aortic atherosclerosis?
Absolute Event Rate: 5.8% vs 3.8%
p-value: p=0.02
Flow-sensitive 4D MRI is a reproducible method for estimating aortic pulse wave velocity, which is elevated in patients with aortic atherosclerosis and correlates with age, aortic valve insufficiency, and pulse pressure.
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4D MRI aortic PWV measurement shows reliability in volunteers; leaves open its prognostic role in atherosclerosis.
Markl et al. (2012) conducted an observational in Aortic atherosclerosis (n=98). Flow-sensitive four-dimensional (4D) MRI vs. Volunteers was evaluated on Aortic pulse wave velocity (PWV) (p=0.02). Aortic pulse wave velocity measured by flow-sensitive 4D MRI was significantly higher in patients with aortic atherosclerosis compared to volunteers (5.8 vs 3.8 m/s; P=0.02).
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