Key result
An electronic health record best practice advisory increased documented guideline-directed medical therapy prescribing from 9.1% to 42.2% in patients with HFrEF.
Why the study?
Does an electronic health record best practice advisory improve guideline-directed medical therapy prescribing in patients with heart failure with reduced ejection fraction?
Does an electronic health record best practice advisory improve guideline-directed medical therapy prescribing in patients with heart failure with reduced ejection fraction?
Absolute Event Rate: 42.2% vs 9.1%
Implementing an electronic health record-based best practice advisory significantly increases the prescribing rates of guideline-directed medical therapy in patients with HFrEF.
EHR advisory was associated with higher GDMT prescribing in HFrEF; hypothesis-generating and should not yet change practice.
In this pre-post Define, Measure, Analyze, Improve, Control quality improvement study, an Epic electronic health record best practice advisory was implemented to prompt guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction. Documented GDMT prescribing rose markedly from 9.1% to 42.2%, supporting electronic health record-based prompts as an effective strategy for GDMT optimization.
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Oquendo et al. (2026) studied Heart failure with reduced ejection fraction. Epic electronic health record best practice advisory vs. Pre-intervention period was evaluated on Documented guideline-directed medical therapy (GDMT) prescribing. An electronic health record best practice advisory increased documented guideline-directed medical therapy prescribing from 9.1% to 42.2% in patients with HFrEF.
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