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July 26, 2026Biochemical Society TransactionsOpen Access

Understanding adipocyte heterogeneity across species, depot, and disease

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Authors

EKElizabeth S. KittoSKShiri KultMEMargo P. Emont

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Overview

Review synthesizes adipocyte subpopulations across different species and conditions, highlighting current gaps in understanding.

Key Points

  • This review aims to clarify the heterogeneity of adipocyte populations across species, fat depots, and metabolic disease.
  • Reviewed recent publications in adipocyte heterogeneity.
  • Synthesized identified adipocyte populations into classes based on predicted functionality.
  • Discussed gaps in functional characterization of these subpopulations.
  • Identified multiple subpopulations of adipocytes linked to specific adipose depots and conditions.
  • Highlighted the importance of advanced RNA sequencing methods in characterizing adipocyte diversity.
  • Pointed out significant gaps in understanding the functionality of newly identified adipocyte groups.

Cite This Study

Kitto et al. (2026) studied this question.

synapsesocial.com/papers/6a65a76fd3aea3239cd7850ehttps://doi.org/10.1042/bst20250327
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