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July 26, 2026Journal of Child and Adolescent Psychopharmacology

Utility of ADHD Medications in Children and Adolescents with Trauma-Related Presentations: A Systematic Scoping Review

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Authors

AIAthif IlyasGKG Narasimha KumarMAMark Addison

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Overview

Systematic review maps ADHD medication effectiveness for trauma-related symptoms in children and adolescents, suggesting optimal approaches.

Key Points

  • This review aimed to evaluate the effectiveness of ADHD medications for children and adolescents with trauma-related symptoms.
  • Conducted a systematic scoping review following Joanna Briggs Institute methodology.
  • Search included Medline, Embase, PsycINFO, and gray literature from January 1985 to November 2025.
  • Findings organized by medication class with narrative synthesis.
  • Alpha-2 agonists (guanfacine and clonidine) consistently improved trauma-related symptoms.
  • Stimulants and atomoxetine showed less consistent improvements, but stimulants reduced hospitalizations and emergency visits.
  • No studies on viloxazine were found, and overall evidence quality is low.

Cite This Study

Ilyas et al. (2026) studied this question.

synapsesocial.com/papers/6a65a84ed3aea3239cd78cdchttps://doi.org/10.1177/10445463261470300
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