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July 26, 2026Current Microwave Chemistry

Aqueous Choline Chloride-Urea DES-Promoted MAE Extraction ofBioactive Compounds from Otostegia limbata Twigs and ProcessOptimization Based on RSM and ANN

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Authors

AYAqsa YounasForman Christian CollegeHIHaroon IftikharForman Christian CollegeDADildar AhmedForman Christian College

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Overview

Randomized trial develops a green extraction method for bioactive compounds from Otostegia limbata, indicating sustainable processing benefits.

Key Points

  • This study aims to optimize a green extraction method for bioactive compounds from Otostegia limbata using microwave-assisted extraction.
  • Employed choline chloride–urea-based aqueous natural deep eutectic solvents as extraction solvents.
  • Optimized extraction parameters using response surface methodology with a focus on microwave power and solid-solvent ratio.
  • Applied artificial neural network modeling for analyzing nonlinear relationships in extraction efficiency.
  • Optimal conditions achieved TPC of 11.44 mg GAE/g DW and TFC of 3.93 mg RE/g DW.
  • DPPH radical scavenging activity reached 2.23 mg AAE/g DW; iron-chelating activity was 52.69 mg EDTAE/g DW.
  • α-amylase inhibitory activity was recorded at 53.18%, confirming the effectiveness of MAE coupled with NaDES.

Cite This Study

Younas et al. (2026) studied this question.

synapsesocial.com/papers/6a65a962d3aea3239cd7943fhttps://doi.org/10.2174/0122133356477777260707074315
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