Key result
In asymptomatic Korean adults, coronary artery calcium score was independently associated with all-cause mortality (HR 1.10) and significantly improved risk prediction over the Framingham risk score.
Why the study?
Does the addition of Coronary Artery Calcium Score (CACS) to traditional risk factors improve the prediction of all-cause mortality in asymptomatic Korean adults?
Population
34,386 asymptomatic Korean adults participating in a general health examination
Comparison
Coronary artery calcium score assessment added… vs Traditional risk factors alone
Design
Cohort
Follow-up
median 4.9 years (IQR, 3.0-7.1)
Authors
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May support CACS for refining mortality risk in asymptomatic Koreans; extends Framingham models but leaves open need for prospective validation.
Observational (n=34,386)
Yes
Does the addition of Coronary Artery Calcium Score (CACS) to traditional risk factors improve the prediction of all-cause mortality in asymptomatic Korean adults?
Hazard Ratio: 1.1 (95% CI 1.05–1.17)
p-value: p=<0.001
In asymptomatic Korean adults, the addition of coronary artery calcium scoring to traditional risk factors significantly improves the prediction of all-cause mortality.
Han et al. (2015) conducted an observational in Asymptomatic adults (n=34,386). Coronary artery calcium score (CACS) vs. Framingham 10-year risk score (FRS) / CACS = 0 was evaluated on All-cause mortality (HR 1.10, 95% CI 1.05-1.17, p=<0.001). In asymptomatic Korean adults, coronary artery calcium score was independently associated with all-cause mortality (HR 1.10) and significantly improved risk prediction over the Framingham risk score.
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