Key result
In asymptomatic Korean adults, the presence of coronary artery calcium was associated with a higher risk of all-cause mortality (adjusted HR 2.20) and a shorter warranty period (5 vs. 9 years) compared to a zero calcium score.
Why the study?
Does a zero coronary artery calcium score predict a longer warranty period against all-cause mortality in asymptomatic adults across different cardiac risk burdens?
Population
48,215 asymptomatic Korean adults
Comparison
Zero coronary artery calcium (CAC=0) score vs Presence of coronary artery calcium (CAC >0)
Design
Cohort
Follow-up
median 4.4 years (IQR, 2.7-6.6)
Authors
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Supports CAC=0 for extended low-mortality warranty in asymptomatic adults; leaves open whether it alters management across risk strata.
Cohort (n=48,215)
Yes
Does a zero coronary artery calcium score predict a longer warranty period against all-cause mortality in asymptomatic adults across different cardiac risk burdens?
Hazard Ratio: 2.2 (95% CI 1.7–2.86)
Absolute Event Rate: 1.4% vs 0.6%
p-value: p=<0.001
In asymptomatic Korean adults, a zero CAC score is associated with a longer warranty period against all-cause mortality, particularly when no other risk factors are present.
Lee et al. (2016) conducted a cohort in Asymptomatic adults (n=48,215). Coronary artery calcium (CAC > 0) vs. Zero coronary artery calcium (CAC = 0) was evaluated on All-cause mortality (HR 2.20, 95% CI 1.70-2.86, p=<0.001). In asymptomatic Korean adults, the presence of coronary artery calcium was associated with a higher risk of all-cause mortality (adjusted HR 2.20) and a shorter warranty period (5 vs. 9 years) compared to a zero calcium score.
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