Randomized trial evaluates lymph node count's effect on survival in colon cancer by tumour location, suggesting varying impacts based on anatomy.
Objectives: The prognostic significance of lymph node (LN) count in colon cancer (CC) remains controversial. Current guidelines recommend retrieval of ≥12 LNs for accurate staging; however, tumour sidedness may influence its prognostic relevance. This study evaluated the impact of LN count on survival according to tumour sidedness and pathological stage (pStage).
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Iguchi et al. (2026) studied this question.
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