Key result
Exposure to coxsackieviruses B1/B5, B3, and B4 was detected in 6.7% to 21.6% of healthy blood donors across Greece, with the highest B1/B5 prevalence in Crete (p=0.025) and B4 in Athens (p=0.01).
Population
506 healthy blood donors from various transfusion centers covering the entire country of Greece
Design
Cross-sectional
Authors
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Indicates substantial coxsackie B exposure across Greece; leaves open its contribution to myocarditis incidence.
Cross-Sectional (n=506)
Yes
There is significant geographic variation in Coxsackievirus B seroprevalence in Greece, which may relate to regional clusters of myocarditis and diabetes.
Mavrouli et al. (2007) conducted a cross-sectional in Healthy blood donors (n=506). Coxsackievirus B exposure was evaluated on Prevalence of IgG and IgM antibodies against coxsackieviruses B1/B5, B3, and B4. Exposure to coxsackieviruses B1/B5, B3, and B4 was detected in 6.7% to 21.6% of healthy blood donors across Greece, with the highest B1/B5 prevalence in Crete (p=0.025) and B4 in Athens (p=0.01).
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