Key result
Coxsackie B virus infection was detected in 75.75% of patients with myocarditis and dilated cardiomyopathy using an IgM-specific immunoassay, with a 6% mortality rate.
Why the study?
Recent data were lacking on extra-intestinal Enterovirus infection, particularly myocarditis and DCM caused by Coxsackie virus B in south India.
Cross-Sectional
There is a high prevalence (75.75%) of recent Coxsackie B virus infection among patients with myocarditis and dilated cardiomyopathy in South India.
Almost 70% of the myocarditis and dilated cardiomyopathy (DCM) cases are found to be caused by Enterovirus genus, the majority of these infections were caused by coxsackie virus B (CVB) group. There is no recent data available on extra-intestinal infection particularly myocarditis and DCM caused by this virus in south India. Presence of IgM antibody specific for CVB in myocarditis and DCM patients were detected using SERION ELISA. The prevalence of Coxsackie B virus among myocarditis and dilated cardiomyopathy patients was found to be 75.75% when tested using an immunoassay specific for IgM antibodies. The mortality rate among study population is found to be 6%.
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Bharathi et al. (2019) conducted a cross-sectional in Myocarditis and dilated cardiomyopathy. Coxsackie B virus infection was evaluated on Prevalence of Coxsackie B virus. Coxsackie B virus infection was detected in 75.75% of patients with myocarditis and dilated cardiomyopathy using an IgM-specific immunoassay, with a 6% mortality rate.
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