Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 29, 2026DiabetologiaOpen Access

Effects of time-restricted eating on markers of glucose metabolism and regulation in individuals with prediabetes or type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials

View Full Paper
Ask AI
Bookmark
Share

Authors

FVFrida VipleSPSofie S. PedersenTATue Helms Andersen

Discussion

Loading...

Member takes

Overview

Randomized trial investigates time-restricted eating impacts on glucose markers in prediabetes and type 2 diabetes, suggesting potential health benefits.

Key Points

  • The study aimed to evaluate the effects of time-restricted eating on glucose metabolism in individuals with prediabetes or type 2 diabetes.
  • Systematic review and meta-analysis of randomised controlled trials
  • Investigated effects of TRE (≤12 h eating window) vs. non–time-restricted control diet
  • Included RCTs with a minimum duration of 2 weeks focusing on glucose metabolism markers
  • TRE did not significantly affect HbA1c in general (−3.33 mmol/mol; p=0.06), but reduced HbA1c by 0.93 mmol/mol in prediabetes (p=0.02)
  • TRE significantly reduced fasting blood glucose overall (−0.30 mmol/l; p<0.01) and in both subgroups: prediabetes (−0.14 mmol/l; p=0.03) and type 2 diabetes (−0.48 mmol/l; p<0.01)
  • TRE lowered body weight by 1.6 kg (p<0.001) overall, indicating beneficial effects on weight management.

Cite This Study

Viple et al. (2026) studied this question.

synapsesocial.com/papers/6a69a26dc8da07d9defa5db1https://doi.org/10.1007/s00125-026-06792-5
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of time-restricted eating on beta-cell function in adults with type 2 diabetes: a randomized cross-over trial2024 · 21 citations
  2. 2The PRISMA 2020 statement: an updated guideline for reporting systematic reviews2021 · 106,426 citations
  3. 3Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: a randomised crossover trial2022 · 126 citations
  4. 4Evolution of the diagnostic value of “the sugar of the blood”: hitting the sweet spot to identify alterations in glucose dynamics2022 · 11 citations
  5. 5Circadian alignment of food intake and glycaemic control by time-restricted eating: A systematic review and meta-analysis2023 · 42 citations