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July 29, 2026Retina

Optical Coherence Tomography Angiography-Guided Laser Management of Neovascular Central Serous Chorioretinopathy

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Authors

DMDmitrii S. MaltsevАКА Н КуликовYKYana A. Kalinicheva

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Overview

Randomized trial analyzes efficacy of OCTA-guided laser treatment in neovascular CSCR, highlighting its safety and effectiveness.

Key Points

  • To evaluate the efficacy and safety of OCTA-guided laser management for neovascular central serous chorioretinopathy.
  • Included 67 patients with neovascular non-resolving CSCR treated with OCTA-guided laser without fluorescein angiography.
  • Patients were treated with microsecond pulsing laser or focal laser photocoagulation over three sessions.
  • Compared with a control group of 30 untreated patients observed for at least six months.
  • Complete resolution of subretinal fluid achieved in 32 eyes (47.8%) in the treatment group versus none in the control group (p < 0.001).
  • Success rate in eyes with fovea-involving CNV was lower (odds ratio 0.21, 95% CI 0.073 to 0.583).
  • Success rate increased to 65.0% after excluding foveal center involvement with no major adverse effects noted.

Cite This Study

Maltsev et al. (2026) studied this question.

synapsesocial.com/papers/6a69a295c8da07d9defa638fhttps://doi.org/10.1097/iae.0000000000004940
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  1. 1Navigated focal laser photocoagulation of choroidal neovascularization in central serous chorioretinopathy2024
  2. 2Short-Term Outcomes of Combined Anti-VEGF and Laser Photocoagulation in Chronic Central Serous Chorioretinopathy2025
  3. 3Argon laser photocoagulation therapy for nonresolving central serous chorioretinopathy2026
  4. 4Central serous chorioretinopathy imaging biomarkers as potential indicators of response to subthreshold nanosecond laser2025
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