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August 1, 2025

Short-Term Outcomes of Combined Anti-VEGF and Laser Photocoagulation in Chronic Central Serous Chorioretinopathy

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Authors

AHA HernándezJAJuan Carlos AltamiranoMAManuel Arias

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Overview

Retrospective study shows combined anti-VEGF and laser treatment improves function and anatomy in cCSC, indicating potential for better patient care.

Key Points

  • Combining anti-VEGF and laser photocoagulation improves anatomical and functional outcomes in cCSC patients.
  • At 1 month, 73.3% of eyes showed complete resolution of subretinal fluid, with 100% resolution at 4 months.
  • BCVA improved significantly from 0.53 to 0.31 over three months, indicating effective visual enhancement.
  • This treatment strategy may offer a new viable option for managing cCSC, pending further long-term studies.

Cite This Study

Hernández et al. (2025) studied this question.

synapsesocial.com/papers/689a0c6be6551bb0af8cfe1ahttps://doi.org/10.21203/rs.3.rs-7181887/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Photodynamic therapy and anti-vascular endothelial growth factor for acute central serous chorioretinopathy: an updated systematic review and meta-analysis2026
  2. 2Comparison between Focal Laser Photocoagulation and Intravitreal Bevacizumab Injection for Treating Chronic Central Serous Chorioretinopathy2024
  3. 3Subthreshold micropulse 520-nm laser for acute central serous chorioretinopathy: short-term outcomes and structural OCT biomarkers2026
  4. 4Comparison of the efficacy of subthreshold micropulse laser versus intravitreal anti-VEGF therapy for chronic central serous chorioretinopathy2026
  5. 5Optical Coherence Tomography Angiography-Guided Laser Management of Neovascular Central Serous Chorioretinopathy2026