What question did this study set out to answer?

This study aimed to determine if staple-line clip reinforcement reduces the incidence of clinically relevant pancreatic fistula after laparoscopic distal pancreatectomy.

July 29, 2026International Journal of Surgery

Routine staple-line clip reinforcement during laparoscopic distal pancreatectomy does not reduce clinically relevant pancreatic fistula: a multicenter randomized clinical trial

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Authors

MSMin Kyu SungAsan Medical Center DSDakyum ShinChosun University Hospital KJKwon JsSeoul National University Bundang Hospital

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Overview

Randomized trial evaluates staple-line clip reinforcement's effect on pancreatic fistula incidence in adults, suggesting a focus on operational efficiency.

Key Points

This study aimed to determine if staple-line clip reinforcement reduces the incidence of clinically relevant pancreatic fistula after laparoscopic distal pancreatectomy.
Multicenter, open-label, randomized clinical trial conducted at three tertiary referral centers.
190 adult patients randomized 1:1 to clip reinforcement or standard stapled transection.
Primary outcome was the incidence of clinically relevant postoperative pancreatic fistula.
CR-POPF occurred in 21.9% of the clip group and 27.7% of the no-clip group (P = 0.45).
No grade C fistulas were reported in either group.
Prolonged operation time identified as an independent risk factor for CR-POPF (adjusted OR 1.012 per minute, P = 0.004).

Cite This Study

Sung et al. (2026) studied this question.

synapsesocial.com/papers/6a69a2e2c8da07d9defa6f37 https://doi.org/10.1097/js9.0000000000005534

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July 29, 2026International Journal of Surgery

Routine staple-line clip reinforcement during laparoscopic distal pancreatectomy does not reduce clinically relevant pancreatic fistula: a multicenter randomized clinical trial

View Full Paper

Ask AI

Bookmark

Authors

MSMin Kyu SungAsan Medical Center DSDakyum ShinChosun University Hospital KJKwon JsSeoul National University Bundang Hospital

Discussion

Member takes

Overview

Randomized trial evaluates staple-line clip reinforcement's effect on pancreatic fistula incidence in adults, suggesting a focus on operational efficiency.

Key Points

This study aimed to determine if staple-line clip reinforcement reduces the incidence of clinically relevant pancreatic fistula after laparoscopic distal pancreatectomy.
Multicenter, open-label, randomized clinical trial conducted at three tertiary referral centers.
190 adult patients randomized 1:1 to clip reinforcement or standard stapled transection.
Primary outcome was the incidence of clinically relevant postoperative pancreatic fistula.
CR-POPF occurred in 21.9% of the clip group and 27.7% of the no-clip group (P = 0.45).
No grade C fistulas were reported in either group.
Prolonged operation time identified as an independent risk factor for CR-POPF (adjusted OR 1.012 per minute, P = 0.004).

Cite This Study

Sung et al. (2026) studied this question.

synapsesocial.com/papers/6a69a2e2c8da07d9defa6f37 https://doi.org/10.1097/js9.0000000000005534

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