Key result
Direct recording of sinus node electrograms via a transvenous catheter yielded sinoatrial conduction times that closely matched indirect estimates.
Why the study?
Does a transvenous electrode catheter technique accurately measure sinoatrial conduction time compared to indirect estimation in adults?
Observational (n=23)
Does a transvenous electrode catheter technique accurately measure sinoatrial conduction time compared to indirect estimation in adults?
A transvenous catheter technique can successfully record direct sinus node electrograms in adults, yielding sinoatrial conduction times that closely match indirect estimates.
Answers are grounded in this paper and cite their sources.
Supports feasibility of transvenous sinus node recording; leaves open its role in refining clinical sinoatrial assessment.
To improve methods for evaluating human sinus node function (SNF), we developed a transvenous electrode catheter technique for direct recording of sinus node electrograms in adults. Sinus node electrograms (SNE) characterized by low-frequency, anatomically localized pre-P-wave potentials were obtained in 19 of 23 patients. The SNE configuration was similar to that previously found for endocardial SNE recordings in in vitro atrial preparations, in open-chest dogs and during human open heart surgery. In 16 patients with normal SNF, directly recorded sinoatrial conduction times (SACTs) were 46-116 msec. In three patients with sick sinus syndrome, SACT was 110-126 msec. In 15 of the 19 patients, SACT was estimated by the atrial premature stimulus technique and was compared with the directly measured SACT. When atrial premature depolarizations produced no sinus node depression, the mean differences between the direct and estimated SACT was 1.8 +/- 5.6 msec.
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Reiffel et al. (1980) conducted an observational in Sinus node function evaluation (n=23). Direct recording of sinus node electrograms via transvenous catheter vs. Indirect estimation via atrial premature stimulus technique was evaluated on Difference between direct and estimated sinoatrial conduction time (MD 1.8). Direct recording of sinus node electrograms via a transvenous catheter yielded sinoatrial conduction times that closely matched indirect estimates.
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