Key result
Classification based solely on maximal creatine kinase MB concentration was the strongest predictor of 1- and 5-year mortality (OR 2.8-3.7, p<0.001) in patients with suspected myocardial infarction.
Why the study?
Does a classification based solely on maximal creatine kinase MB concentration predict mortality better than the MONICA criteria in patients with suspected acute myocardial infarction?
Population
311 consecutive patients evaluated for suspected acute myocardial infarction in a regional referral hospital
Comparison
Patient classification based solely on the… vs MONICA criteria and a simplified code combining…
Design
Cohort
Follow-up
1 and 5 years
Authors
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CK-MB classification may refine mortality risk stratification in suspected MI; leaves open superiority over MONICA criteria in prospective studies.
Cohort (n=311)
No
Does a classification based solely on maximal creatine kinase MB concentration predict mortality better than the MONICA criteria in patients with suspected acute myocardial infarction?
Effect estimate: OR 2.8-3.7
p-value: p=<0.001
Classification of suspected acute myocardial infarction based solely on creatine kinase MB mass provides strong prognostic information for 1- and 5-year mortality.
Pekka Porela (1999) conducted a cohort in suspected acute myocardial infarction (n=311). Creatine kinase MB based classification vs. MONICA criteria was evaluated on Total mortality at 1 and 5 years (OR 2.8-3.7, p=<0.001). Classification based solely on maximal creatine kinase MB concentration was the strongest predictor of 1- and 5-year mortality (OR 2.8-3.7, p<0.001) in patients with suspected myocardial infarction.
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