Key result
Maximum systolic blood pressure during exercise was highly correlated with ECG signs of left ventricular hypertrophy (r=0.496, p<0.001) and normalized left ventricular mass (r=0.609, p<0.005).
Why the study?
Does a greater blood pressure response during exercise correlate with a tendency to develop left ventricular hypertrophy in subjects with high-normal resting blood pressure?
Observational (n=54)
Does a greater blood pressure response during exercise correlate with a tendency to develop left ventricular hypertrophy in subjects with high-normal resting blood pressure?
Effect estimate: r = 0.496
p-value: p=<0.001
A greater blood pressure response during submaximal exercise is associated with a tendency to develop left ventricular hypertrophy in individuals with high-normal resting blood pressure.
Supports exercise BP-LVH association in high-normal BP; hypothesis-generating, needs prospective validation before practice change.
From among subjects who were examined by submaximal exercise testing in 1987, 54 were selected in order to examine the relationship between the blood pressure response during exercise and the tendency to develop left ventricular hypertrophy. Only those subjects having resting systolic blood pressure values between 120 mmHg and 140 mmHg were selected. The maximum systolic blood pressure during submaximal exercise was highly correlated with the sum of the R wave amplitude in V5 and the S wave amplitude in V1 of the resting ECG (r = 0.496, p less than 0.001, n = 54), as well as with the left ventricular mass normalized for body surface area (r = 0.609, p less than 0.005, n = 23). The maximum systolic blood pressure measured during submaximal exercise did not correlate with age or exercise duration. These results suggest that a greater blood pressure response during exercise is related to the tendency to develop left ventricular hypertrophy.
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Taguchi et al. (1990) conducted an observational in Left ventricular hypertrophy (n=54). Maximum systolic blood pressure during submaximal exercise was evaluated on Sum of R wave amplitude in V5 and S wave amplitude in V1 of resting ECG (r = 0.496, p=<0.001). Maximum systolic blood pressure during exercise was highly correlated with ECG signs of left ventricular hypertrophy (r=0.496, p<0.001) and normalized left ventricular mass (r=0.609, p<0.005).
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