Key result
In unmedicated men with mild hypertension, systolic blood pressure at peak exercise was strongly correlated with left ventricular mass index (r=0.57) and was the strongest predictor of its progression over 5 years.
Why the study?
Does systolic blood pressure at peak exercise predict the progression of left ventricular hypertrophy in unmedicated men with mild hypertension?
Population
155 unmedicated male subjects with borderline and mild hypertension
Design
Cohort
Follow-up
5 years
Authors
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May inform LVH risk stratification in mild hypertension; leaves open whether targeting peak SBP alters progression.
Cohort (n=155)
No
Does systolic blood pressure at peak exercise predict the progression of left ventricular hypertrophy in unmedicated men with mild hypertension?
Effect estimate: r=0.57
p-value: p=<0.001
Systolic blood pressure at peak exercise is a simple and reliable predictor of left ventricular hypertrophy progression in unmedicated men with mild hypertension.
Tomiyama et al. (1992) conducted a cohort in Mild hypertension (n=155). Systolic blood pressure at peak exercise (max Ps) vs. Normal blood pressure response to exercise (max Ps < 200 mmHg) was evaluated on Correlation between systolic blood pressure at peak exercise and left ventricular mass index (LVMI) (r=0.57, p=<0.001). In unmedicated men with mild hypertension, systolic blood pressure at peak exercise was strongly correlated with left ventricular mass index (r=0.57) and was the strongest predictor of its progression over 5 years.
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