Key result
Left ventricular hypertrophy in mild hypertension is multifactorial, and its progression can be predicted by a left ventricular mass index >124 g/m2 and peak systolic pressure >200 mmHg during maximal exercise testing.
Why the study?
Does antihypertensive treatment regress left ventricular hypertrophy and improve physical fitness in patients with mild essential hypertension?
Population
Patients with borderline or mild essential hypertension
Comparison
Antihypertensive medications vs Unmedicated observation or alternative…
Design
Review
Follow-up
Up to 5 years (for observational cohorts discussed)
Authors
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May aid risk stratification by exercise testing in mild hypertension; hypothesis-generating for tailored LVH prevention pending prospective trials.
Does antihypertensive treatment regress left ventricular hypertrophy and improve physical fitness in patients with mild essential hypertension?
In mild hypertension, LVH progression is predictable by exercise hemodynamics and LVMI, and while both calcium channel blockers and beta-blockers regress LVH, they have divergent effects on physical fitness.
Doba et al. (1996) conducted a review in Mild essential hypertension. Antihypertensive treatment strategies was evaluated. Left ventricular hypertrophy in mild hypertension is multifactorial, and its progression can be predicted by a left ventricular mass index >124 g/m2 and peak systolic pressure >200 mmHg during maximal exercise testing.
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