Key result
Nonagenarian patients undergoing TAVI had higher 30-day all-cause mortality compared to patients <90 years (15.6% vs. 8.4%; p=0.04), though 1-year mortality was similar (20.9% vs. 21.8%).
Why the study?
Does TAVI result in different mortality outcomes in nonagenarian patients compared to younger patients with symptomatic severe aortic stenosis?
Population
819 patients with symptomatic severe aortic stenosis enrolled in the Brazilian multicenter registry.
Comparison
Transcatheter aortic valve implantation in… vs Transcatheter aortic valve implantation in…
Design
Cohort
Follow-up
2 years
Authors
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Nonagenarians face higher 30-day TAVI mortality risk; this cohort study leaves open optimal age-based selection criteria.
Cohort (n=819)
Yes
Does TAVI result in different mortality outcomes in nonagenarian patients compared to younger patients with symptomatic severe aortic stenosis?
Absolute Event Rate: 15.6% vs 8.4%
p-value: p=0.04
TAVI in nonagenarians is associated with higher 30-day and 2-year mortality compared to younger patients, though 1-year mortality rates appear similar.
Helber et al. (2017) conducted a cohort in symptomatic severe aortic stenosis (n=819). Age ≥90 years (nonagenarian) vs. Age <90 years was evaluated on 30-day all-cause mortality (p=0.04). Nonagenarian patients undergoing TAVI had higher 30-day all-cause mortality compared to patients <90 years (15.6% vs. 8.4%; p=0.04), though 1-year mortality was similar (20.9% vs. 21.8%).
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